Hierarchical study of Guyton Circulatory Model

Increase in Mean Circulatory Pressure in Goldblatt Hypertension.

RICHARDSON, TRAVIS Q., JOSE D. FERMOSO, AND ARTHUR C. GUYTON. Increase in mean circulatory pressure in Goldblatt hypertension. Am. J. Physiol. 207(4): 751-752. rg6+-Ten dogs were made hypertensive by the Goldblatt technique. The mean arterial pressure increased from an average control value of I I 7 mm Hg up to I 61 mm Hg. After the animals had become hypertensive, the mean circulatory pressure...

A quantitative approach to the study of circulatory abnormality, especially of hypertension.

Clinical review: Guyton - the role of mean circulatory filling pressure and right atrial pressure in controlling cardiac output

Arthur Guyton's concepts of the determinative role of right heart filling in cardiac output continue to be controversial. This paper reviews his seminal experiments in detail and clarifies the often confusing concepts underpinning his model. One primary criticism of Guyton's model is that the parameters describing venous return had not been measured in a functioning cardiovascular system in hum...

Essential Hypertension: An Approach to Clinical Data by the Use of Models

A new approach, based on animal circulatory models, was proposed for the study of clinical data in hypertension. Clinical data were identified with steady states in models. From the study of models, possible impairments, susceptible to account for the observed deviations of steady states in men, were analyzed. To be specific, the 1967-Guyton-Coleman model was confronted with a set of data on es...

A New Minimum Order Lumped-Parameter Model of Circulatory System for Patients with Suffered Left and Right-Sided Heart Failure

In this study a new minimum lumped electrical model of total circulatory system through numerical solutions to approximate the response of the human circulatory system was presented. Among five existent ventricular elastances as activity function of heart pumps, a more accurate model was chosen as well as the operation of baroreflex system to accommodate variations in heart rate and systemic va...